6HCJ
Structure of the rabbit 80S ribosome on globin mRNA in the rotated state with A/P and P/E tRNAs
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | 51 | 28S ribosomal RNA | polymer | 3635 | 1177882.3 | 1 | Oryctolagus cuniculus | ||
| 2 | 71 | 5S ribosomal RNA | polymer | 120 | 38691.9 | 1 | Oryctolagus cuniculus | ||
| 3 | 81 | 5.8S ribosomal RNA | polymer | 156 | 50143.6 | 1 | Oryctolagus cuniculus | ||
| 4 | A2 | 18S ribosomal RNA | polymer | 1869 | 602779.8 | 1 | Oryctolagus cuniculus | ||
| 5 | B2 | uS2 | polymer | 295 | 32958.0 | 1 | Oryctolagus cuniculus | ||
| 6 | C2 | 40S ribosomal protein S3a | polymer | 264 | 30002.1 | 1 | UniProt (G1SS70) Pfam (PF01015) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 7 | D2 | uS5 | polymer | 293 | 31327.4 | 1 | Oryctolagus cuniculus | ||
| 8 | E2 | uS3 | polymer | 243 | 26715.3 | 1 | UniProt (G1TNM3) Pfam (PF07650) Pfam (PF00189) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 9 | F2 | eS4 | polymer | 263 | 29654.9 | 1 | Oryctolagus cuniculus | ||
| 10 | G2 | Ribosomal protein S5 | polymer | 204 | 22913.5 | 1 | UniProt (G1TFM5) Pfam (PF00177) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 11 | H2 | 40S ribosomal protein S6 | polymer | 249 | 28751.9 | 1 | UniProt (G1TM55) Pfam (PF01092) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 12 | I2 | 40S ribosomal protein S7 | polymer | 194 | 22168.9 | 1 | UniProt (G1SVB0) Pfam (PF01251) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 13 | J2 | eS8 | polymer | 208 | 24263.4 | 1 | Oryctolagus cuniculus | ||
| 14 | K2 | Ribosomal protein S9 (Predicted) | polymer | 194 | 22641.6 | 1 | UniProt (B7NZS8) Pfam (PF00163) Pfam (PF01479) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 15 | L2 | eS10 | polymer | 165 | 18933.8 | 1 | UniProt (G1TPV3) Pfam (PF03501) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 16 | M2 | Ribosomal protein S11 | polymer | 158 | 18468.8 | 1 | UniProt (G1TRM4) Pfam (PF16205) Pfam (PF00366) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 17 | N2 | 40S ribosomal protein S12 | polymer | 132 | 14539.0 | 1 | UniProt (G1SFR8) Pfam (PF01248) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 18 | O2 | uS15 | polymer | 151 | 17259.4 | 1 | UniProt (G1SP51) Pfam (PF08069) Pfam (PF00312) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 19 | P2 | uS11 | polymer | 168 | 18134.0 | 1 | Oryctolagus cuniculus | ||
| 20 | Q2 | uS19 | polymer | 145 | 17049.2 | 1 | UniProt (G1U0Q2) Pfam (PF00203) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 21 | R2 | Ribosomal protein S16 | polymer | 146 | 16477.4 | 1 | UniProt (G1SGX4) Pfam (PF00380) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 22 | S2 | eS17 | polymer | 135 | 15552.1 | 1 | UniProt (G1TU13) Pfam (PF00833) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 23 | T2 | uS13 | polymer | 152 | 17759.8 | 1 | UniProt (G1TPG3) Pfam (PF00416) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 24 | U2 | eS19 | polymer | 145 | 16106.6 | 1 | Oryctolagus cuniculus | ||
| 25 | V2 | uS10 | polymer | 119 | 13398.8 | 1 | UniProt (G1SIZ2) Pfam (PF00338) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 26 | W2 | eS21 | polymer | 83 | 9124.4 | 1 | Oryctolagus cuniculus | ||
| 27 | X2 | Ribosomal protein S15a | polymer | 130 | 14865.6 | 1 | UniProt (G1TG89) Pfam (PF00410) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 28 | Y2 | uS12 | polymer | 143 | 15844.7 | 1 | Oryctolagus cuniculus | ||
| 29 | Z2 | eS24 | polymer | 130 | 15107.9 | 1 | Oryctolagus cuniculus | ||
| 30 | a2 | eS25 | polymer | 125 | 13776.2 | 1 | UniProt (G1TDB3) Pfam (PF03297) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 31 | b2 | eS26 | polymer | 115 | 13047.5 | 1 | Oryctolagus cuniculus | ||
| 32 | c2 | 40S ribosomal protein S27 | polymer | 84 | 9480.2 | 1 | UniProt (G1TZ76) Pfam (PF01667) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 33 | d2 | Ribosomal protein S28 | polymer | 69 | 7855.1 | 1 | UniProt (G1TIB4) Pfam (PF01200) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 34 | e2 | uS14 | polymer | 56 | 6690.8 | 1 | UniProt (G1U7M4) Pfam (PF00253) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 35 | f2 | 40S ribosomal protein S30 | polymer | 133 | 14498.9 | 1 | UniProt (G1T8A2) Pfam (PF00240) Pfam (PF04758) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 36 | g2 | Ribosomal protein S27a | polymer | 156 | 18004.0 | 1 | UniProt (G1SK22) Pfam (PF00240) Pfam (PF01599) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 37 | h2 | RACK1 | polymer | 317 | 35115.7 | 1 | UniProt (G1SJB4) Pfam (PF00400) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 38 | A3 | Ribosomal protein L8 | polymer | 257 | 28088.9 | 1 | UniProt (G1TT27) Pfam (PF00181) Pfam (PF03947) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 39 | B3 | uL3 | polymer | 403 | 46108.0 | 1 | UniProt (G1TL06) Pfam (PF00297) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 40 | C3 | uL4 | polymer | 425 | 47727.6 | 1 | Oryctolagus cuniculus | ||
| 41 | D3 | 60S ribosomal protein L5 | polymer | 297 | 34481.8 | 1 | UniProt (G1SYJ6) Pfam (PF17144) Pfam (PF14204) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 42 | E3 | 60S ribosomal protein L6 | polymer | 291 | 33028.3 | 1 | UniProt (G1SKF7) Pfam (PF01159) Pfam (PF03868) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 43 | F3 | uL30 | polymer | 247 | 29201.8 | 1 | UniProt (G1TUB1) Pfam (PF08079) Pfam (PF00327) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 44 | G3 | eL8 | polymer | 319 | 36221.5 | 1 | Oryctolagus cuniculus | ||
| 45 | H3 | uL6 | polymer | 192 | 21871.4 | 1 | UniProt (G1TX33) Pfam (PF00347) UniProt (by SIFTS) (G1SWI6) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 46 | I3 | 60S ribosomal protein L10 | polymer | 214 | 24643.1 | 1 | UniProt (B7NZQ2) Pfam (PF00252) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein L10 (Predicted) |
| 47 | J3 | Ribosomal protein L11 | polymer | 178 | 20288.5 | 1 | UniProt (G1TUB8) Pfam (PF00281) Pfam (PF00673) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 48 | L3 | eL13 | polymer | 211 | 24331.7 | 1 | Oryctolagus cuniculus | ||
| 49 | M3 | Ribosomal protein L14 | polymer | 218 | 23870.5 | 1 | UniProt (G1SZ12) Pfam (PF01929) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 50 | N3 | Ribosomal protein L15 | polymer | 204 | 24207.3 | 1 | UniProt (G1T0C1) Pfam (PF00827) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 51 | O3 | uL13 | polymer | 203 | 23533.3 | 1 | Oryctolagus cuniculus | ||
| 52 | P3 | uL22 | polymer | 184 | 21444.2 | 1 | UniProt (G1TVT6) Pfam (PF00237) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 53 | Q3 | eL18 | polymer | 188 | 21699.7 | 1 | Oryctolagus cuniculus | ||
| 54 | R3 | eL19 | polymer | 196 | 23535.3 | 1 | Oryctolagus cuniculus | ||
| 55 | S3 | eL20 | polymer | 176 | 20827.6 | 1 | Oryctolagus cuniculus | ||
| 56 | T3 | eL21 | polymer | 160 | 18610.0 | 1 | UniProt (G1SHQ2) Pfam (PF01157) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 57 | U3 | eL22 | polymer | 128 | 14813.0 | 1 | Oryctolagus cuniculus | ||
| 58 | V3 | Ribosomal protein L23 | polymer | 140 | 14892.5 | 1 | UniProt (G1T6D1) Pfam (PF00238) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 59 | X3 | uL23 | polymer | 156 | 17768.2 | 1 | UniProt (G1SE76) Pfam (PF03939) Pfam (PF00276) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 60 | Y3 | Ribosomal protein L26 | polymer | 145 | 17303.4 | 1 | UniProt (G1SQH0) Pfam (PF16906) Pfam (PF00467) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 61 | Z3 | 60S ribosomal protein L27 | polymer | 136 | 15835.8 | 1 | UniProt (G1TXF6) Pfam (PF00467) Pfam (PF01777) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 62 | a3 | uL15 | polymer | 148 | 16620.6 | 1 | UniProt (G1SNY0) Pfam (PF00828) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 63 | b3 | eL29 | polymer | 245 | 26708.7 | 1 | UniProt (G1SGR6) Pfam (PF01779) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 64 | c3 | eL30 | polymer | 115 | 12807.1 | 1 | UniProt (G1TDL2) Pfam (PF01248) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 65 | d3 | eL31 | polymer | 125 | 14494.9 | 1 | UniProt (G1SHG0) Pfam (PF01198) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 66 | e3 | eL32 | polymer | 135 | 15898.9 | 1 | UniProt (G1U437) Pfam (PF01655) UniProt (by SIFTS) (G1TUN8) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 67 | f3 | eL33 | polymer | 110 | 12580.8 | 1 | UniProt (G1SF08) Pfam (PF01247) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 68 | g3 | eL34 | polymer | 117 | 13326.1 | 1 | Oryctolagus cuniculus | ||
| 69 | h3 | uL29 | polymer | 123 | 14566.6 | 1 | UniProt (G1SIT5) Pfam (PF00831) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 70 | i3 | 60S ribosomal protein L36 | polymer | 105 | 12263.8 | 1 | UniProt (G1TTQ5) Pfam (PF01158) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 71 | j3 | Ribosomal protein L37 | polymer | 97 | 11111.0 | 1 | UniProt (U3KPD5) Pfam (PF01907) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 72 | k3 | eL38 | polymer | 70 | 8238.9 | 1 | Oryctolagus cuniculus | ||
| 73 | l3 | eL39 | polymer | 51 | 6455.8 | 1 | UniProt (G1TTN1) Pfam (PF00832) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 74 | m3 | eL40 | polymer | 102 | 11699.8 | 1 | Oryctolagus cuniculus | ||
| 75 | n3 | eL41 | polymer | 25 | 3473.5 | 1 | Oryctolagus cuniculus | ||
| 76 | o3 | eL42 | polymer | 106 | 12477.0 | 1 | Oryctolagus cuniculus | ||
| 77 | p3 | eL43 | polymer | 92 | 10299.4 | 1 | UniProt (G1SY53) Pfam (PF01780) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 78 | r3 | eL28 | polymer | 137 | 15783.6 | 1 | UniProt (G1U7L1) Pfam (PF01778) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 79 | q3 | A/P RNA | polymer | 74 | 23874.2 | 1 | Oryctolagus cuniculus | ||
| 80 | t3 | uL10 | polymer | 318 | 34380.5 | 1 | Oryctolagus cuniculus | ||
| 81 | u3 | Ribosomal protein L12 | polymer | 165 | 17847.6 | 1 | UniProt (G1SMR7) Pfam (PF03946) Pfam (PF00298) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 82 | v3 | mRNA | polymer | 22 | 6972.1 | 1 | Oryctolagus cuniculus | ||
| 83 | 33 | P/E tRNA | polymer | 75 | 24231.5 | 1 | Oryctolagus cuniculus | ||
| 84 | w3 | uL1 | polymer | 217 | 24879.4 | 1 | UniProt (G1SKZ8) Pfam (PF00687) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 85 | 1 | nascent chain | polymer | 22 | 1581.7 | 1 | Oryctolagus cuniculus | ||
| 86 | 51, 71, A2, q3, 81... | MAGNESIUM ION | non-polymer | 24.3 | 300 | Chemie (MG) | |||
| 87 | o3, p3, b2, e2, g2... | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) |
Sequence modifications
B3: 2 - 403 (UniProt: G1TL06)
D3: 2 - 297 (UniProt: G1SYJ6)
F3: 1 - 247 (UniProt: G1TUB1)
a3: 2 - 148 (UniProt: G1SNY0)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Arg 61 | Gly 61 | conflict |
| Arg 93 | Gly 93 | conflict |
| Met 131 | Val 131 | conflict |
| Ile 153 | Val 153 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 85 |
| Total formula weight | 3454891.3 | |
| Non-Polymers* | Number of molecules | 308 |
| Total formula weight | 7814.8 | |
| All* | Total formula weight | 3462706.1 |
