6HAD

Human transketolase variant E160Q

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Transketolase	polymer	637	69646.5	1	UniProt (P29401) Pfam (PF00456) Pfam (PF02779) Pfam (PF02780)	Homo sapiens (Human)
2	B (A)	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
3	C (A)	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)
4	D (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
5	E (A)	THIAMINE DIPHOSPHATE	non-polymer		425.3	1	Chemie (TPP)
6	F (A)	water	water		18.0	697	Chemie (HOH)

Sequence modifications

A: 1 - 623 (UniProt: P29401)

PDB	External Database	Details
Gln 160	Glu 160	engineered mutation
Leu 624	-	expression tag
Val 625	-	expression tag
Pro 626	-	expression tag
Arg 627	-	expression tag
Gly 628	-	expression tag
Ser 629	-	expression tag
Leu 630	-	expression tag
Glu 631	-	expression tag
His 632	-	expression tag
His 633	-	expression tag
His 634	-	expression tag
His 635	-	expression tag
His 636	-	expression tag
His 637	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	69646.5
Non-Polymers*	Number of molecules	4
	Total formula weight	512.7
All*	Total formula weight	70159.2

*Water molecules are not included.