6HA3
Human transketolase variant E160Q in covalent complex with donor ketose D-fructose-6-phosphate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Transketolase | polymer | 637 | 69646.5 | 1 | UniProt (P29401) Pfam (PF00456) Pfam (PF02779) Pfam (PF02780) In PDB | Homo sapiens (Human) | TK |
2 | A | 2-C-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium-2-yl}-6-O-phosphono-D-glucitol | non-polymer | 685.5 | 1 | Chemie (T6F) | |||
3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 12 | Chemie (EDO) | |||
4 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
5 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
6 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
7 | water | water | 18.0 | 663 | Chemie (HOH) |
Sequence modifications
A: 1 - 623 (UniProt: P29401)
PDB | External Database | Details |
---|---|---|
Gln 160 | Glu 160 | engineered mutation |
Leu 624 | - | expression tag |
Val 625 | - | expression tag |
Pro 626 | - | expression tag |
Arg 627 | - | expression tag |
Gly 628 | - | expression tag |
Ser 629 | - | expression tag |
Leu 630 | - | expression tag |
Glu 631 | - | expression tag |
His 632 | - | expression tag |
His 633 | - | expression tag |
His 634 | - | expression tag |
His 635 | - | expression tag |
His 636 | - | expression tag |
His 637 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 69646.5 | |
Non-Polymers* | Number of molecules | 16 |
Total formula weight | 1517.6 | |
All* | Total formula weight | 71164.1 |