6H8R
CRYSTAL STRUCTURE OF THE HUMAN PROTEIN TYROSINE PHOSPHATASE PTPN5 (STEP) IN COMPLEX WITH COMPOUND 2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Tyrosine-protein phosphatase non-receptor type 5 | polymer | 305 | 35204.8 | 1 | UniProt (P54829) Pfam (PF00102) In PDB | Homo sapiens (Human) | Neural-specific protein-tyrosine phosphatase,Striatum-enriched protein-tyrosine phosphatase,STEP |
2 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
3 | A | 3-[(2~{S})-2-azanylpropyl]-5-(trifluoromethyl)phenol | non-polymer | 219.2 | 1 | Chemie (FWB) | |||
4 | water | water | 18.0 | 377 | Chemie (HOH) |
Sequence modifications
A: 282 - 563 (UniProt: P54829)
PDB | External Database | Details |
---|---|---|
Met -23 | - | initiating methionine |
His -22 | - | expression tag |
His -21 | - | expression tag |
His -20 | - | expression tag |
His -19 | - | expression tag |
His -18 | - | expression tag |
His -17 | - | expression tag |
Ser -16 | - | expression tag |
Ser -15 | - | expression tag |
Gly -14 | - | expression tag |
Val -13 | - | expression tag |
Asp -12 | - | expression tag |
Leu -11 | - | expression tag |
Gly -10 | - | expression tag |
Thr -9 | - | expression tag |
Glu -8 | - | expression tag |
Asn -7 | - | expression tag |
Leu -6 | - | expression tag |
Tyr -5 | - | expression tag |
Phe -4 | - | expression tag |
Gln -3 | - | expression tag |
Ser -2 | - | expression tag |
Met -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 35204.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 315.3 | |
All* | Total formula weight | 35520.1 |