6H64

Crystal structure of the CRD-SAT

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Galectin-3	polymer	170	18836.4	6	UniProt (P17931) Pfam (PF00337) In PDB	Homo sapiens (Human)	Gal-3,35 kDa lectin,Carbohydrate-binding protein 35,CBP 35,Galactose-specific lectin 3,Galactoside-binding protein,GALBP,IgE-binding protein,L-31,Laminin-binding protein,Lectin L-29,Mac-2 antigen
2	G, H, I, J, K...	beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose	branched		342.3	6	In PDB BIRD (PRD_900008) GlyTouCan (G88362QR)		alpha-lactose
3	A, B, C, D, E...	SULFATE ION	non-polymer		96.1	9	Chemie (SO4)
4		water	water		18.0	457	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 96 - 250 (UniProt: P17931)

PDB	External Database	Details
Met 95	-	initiating methionine
Lys 129	Arg 129	engineered mutation
Thr 245	Ala 245	engineered mutation
Ser 251	-	expression tag
Ser 252	-	expression tag
Gly 253	-	expression tag
Val 254	-	expression tag
Asp 255	-	expression tag
Leu 256	-	expression tag
Gly 257	-	expression tag
Thr 258	-	expression tag
Glu 259	-	expression tag
Asn 260	-	expression tag
Leu 261	-	expression tag
Tyr 262	-	expression tag
Phe 263	-	expression tag
Gln 264	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	113018.6
Branched	Number of molecules	6
	Total formula weight	2053.8
Non-Polymers*	Number of molecules	9
	Total formula weight	864.6
All*	Total formula weight	115936.9

*Water molecules are not included.