6H5A
Crystal structure of Mycobacterium tuberculosis phosphatidylinositol phosphate synthase (PgsA1) in complex with manganese and citrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | CDP-diacylglycerol--inositol 3-phosphatidyltransferase | polymer | 223 | 24069.4 | 2 | UniProt (P9WPG7) Pfam (PF01066) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | Phosphatidylinositol synthase,PI synthase |
| 2 | C, D, E, F, M... (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 7 | Chemie (MN) | |||
| 3 | G, H, P (A, B) | CITRATE ANION | non-polymer | 189.1 | 3 | Chemie (FLC) | |||
| 4 | I, J, Q (A, B) | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | non-polymer | 356.5 | 3 | Chemie (OLC) | |||
| 5 | K, L, S, V (A, B) | EICOSANE | non-polymer | 282.5 | 4 | Chemie (LFA) | |||
| 6 | R (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 7 | T, U (B) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 2 | Chemie (1PE) | |||
| 8 | W, X (A, B) | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 217 (UniProt: P9WPG7)
| PDB | External Database | Details |
|---|---|---|
| Glu 218 | - | expression tag |
| Asn 219 | - | expression tag |
| Leu 220 | - | expression tag |
| Tyr 221 | - | expression tag |
| Phe 222 | - | expression tag |
| Gln 223 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48138.7 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 3724.3 | |
| All* | Total formula weight | 51863.0 |
