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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

6H58

Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein S1 - Full 100S Hibernating E. coli Ribosome

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, EB
(0, 00)		50S ribosomal protein L32polymer566332.22UniProt (P0A7N4)
Pfam (PF01783)		Escherichia coli BW25113Large ribosomal subunit protein bL32
2B, FB
(1, 11)		50S ribosomal protein L33polymer505814.82UniProt (P0A7N9)
Pfam (PF00471)		Escherichia coli BW25113Large ribosomal subunit protein bL33
3C, GB
(2, 22)		50S ribosomal protein L34polymer465397.52UniProt (P0A7P5)
Pfam (PF00468)		Escherichia coli BW25113Large ribosomal subunit protein bL34
4D, HB
(3, 33)		50S ribosomal protein L35polymer647181.82UniProt (P0A7Q1)
Pfam (PF01632)		Escherichia coli BW25113Large ribosomal subunit protein bL35,Ribosomal protein A
5E, IB
(4, 44)		50S ribosomal protein L36polymer384377.42UniProt (P0A7Q6)
Pfam (PF00444)		Escherichia coli BW25113Large ribosomal subunit protein bL36-A,Ribosomal protein B
6F, JB
(6, 66)		50S ribosomal protein L31polymer667516.72UniProt (P0A7M9)
Pfam (PF01197)		Escherichia coli BW25113Large ribosomal subunit protein bL31-A
7G, KB
(A, AA)		23S ribosomal RNApolymer2903941305.32GenBank (1036415628)Escherichia coli BW25113
8H, LB
(B, BB)		5S ribosomal RNApolymer12038813.12GenBank (1393501787)Escherichia coli BW25113
9I, MB
(C, CC)		50S ribosomal protein L2polymer27129663.22UniProt (P60422)
Pfam (PF00181)
Pfam (PF03947)		Escherichia coli BW25113Large ribosomal subunit protein uL2
10J, NB
(D, DD)		50S ribosomal protein L3polymer20922277.52UniProt (P60438)
Pfam (PF00297)		Escherichia coli BW25113Large ribosomal subunit protein uL3
11K, OB
(E, EE)		50S ribosomal protein L4polymer20122121.62UniProt (P60723)
Pfam (PF00573)		Escherichia coli BW25113Large ribosomal subunit protein uL4
12L, PB
(F, FF)		50S ribosomal protein L5polymer17720073.22UniProt (P62399)
Pfam (PF00281)
Pfam (PF00673)		Escherichia coli BW25113Large ribosomal subunit protein uL5
13M, QB
(G, GG)		50S ribosomal protein L6polymer17618801.62UniProt (P0AG55)
Pfam (PF00347)		Escherichia coli BW25113Large ribosomal subunit protein uL6
14N, RB
(H, HH)		50S ribosomal protein L9polymer14915789.02UniProt (P0A7R1)
Pfam (PF01281)
Pfam (PF03948)		Escherichia coli BW25113Large ribosomal subunit protein bL9
15O, SB
(J, JJ)		50S ribosomal protein L13polymer14216050.62UniProt (P0AA10)
Pfam (PF00572)		Escherichia coli BW25113Large ribosomal subunit protein uL13
16P, TB
(K, KK)		50S ribosomal protein L14polymer12213451.92UniProt (P0ADY3)
Pfam (PF00238)		Escherichia coli BW25113Large ribosomal subunit protein uL14
17Q, UB
(L, LL)		50S ribosomal protein L15polymer14314877.32UniProt (P02413)
Pfam (PF00828)		Escherichia coli BW25113Large ribosomal subunit protein uL15
18R, VB
(M, MM)		50S ribosomal protein L16polymer13615312.32UniProt (P0ADY7)
Pfam (PF00252)		Escherichia coli BW25113Large ribosomal subunit protein uL16
19S, WB
(N, NN)		50S ribosomal protein L17polymer12013721.92UniProt (P0AG44)
Pfam (PF01196)		Escherichia coli BW25113Large ribosomal subunit protein bL17
20T, XB
(O, OO)		50S ribosomal protein L18polymer11612663.52UniProt (P0C018)
Pfam (PF00861)		Escherichia coli BW25113Large ribosomal subunit protein uL18
21U, YB
(P, PP)		50S ribosomal protein L19polymer11413028.12UniProt (P0A7K6)
Pfam (PF01245)		Escherichia coli BW25113Large ribosomal subunit protein bL19
22V, ZB
(Q, QQ)		50S ribosomal protein L20polymer11713396.82UniProt (P0A7L3)
Pfam (PF00453)		Escherichia coli BW25113Large ribosomal subunit protein bL20
23AC, W
(R, RR)		50S ribosomal protein L21polymer10311586.42UniProt (P0AG48)
Pfam (PF00829)		Escherichia coli BW25113Large ribosomal subunit protein bL21
24BC, X
(S, SS)		50S ribosomal protein L22polymer11012253.42UniProt (P61175)
Pfam (PF00237)		Escherichia coli BW25113Large ribosomal subunit protein uL22
25CC, Y
(T, TT)		50S ribosomal protein L23polymer9310546.52UniProt (P0ADZ0)
Pfam (PF00276)		Escherichia coli BW25113Large ribosomal subunit protein uL23
26DC, Z
(U, UU)		50S ribosomal protein L24polymer10211078.92UniProt (P60624)
Pfam (PF00467)
Pfam (PF17136)		Escherichia coli BW25113Large ribosomal subunit protein uL24
27AA, EC
(V, VV)		50S ribosomal protein L25polymer9410713.52UniProt (P68919)
Pfam (PF01386)		Escherichia coli BW25113Large ribosomal subunit protein bL25
28BA, FC
(W, WW)		50S ribosomal protein L27polymer758174.42UniProt (P0A7L8)
Pfam (PF01016)		Escherichia coli BW25113Large ribosomal subunit protein bL27
29CA, GC
(X, XX)		50S ribosomal protein L28polymer778896.42UniProt (P0A7M2)
Pfam (PF00830)		Escherichia coli BW25113Large ribosomal subunit protein bL28
30DA, HC
(Y, YY)		50S ribosomal protein L29polymer637286.52UniProt (P0A7M6)
Pfam (PF00831)		Escherichia coli BW25113Large ribosomal subunit protein uL29
31EA, IC
(Z, ZZ)		50S ribosomal protein L30polymer586423.62UniProt (P0AG51)
Pfam (PF00327)		Escherichia coli BW25113Large ribosomal subunit protein uL30
32FA, JC
(a, aa)		16S ribosomal RNApolymer1539498725.42GenBank (1359176725)Escherichia coli BW25113
33GA, KC
(b, bb)		30S ribosomal protein S2polymer22625096.82UniProt (P0A7V0)
Pfam (PF00318)		Escherichia coli BW25113Small ribosomal subunit protein uS2
34HA, LC
(c, cc)		30S ribosomal protein S3polymer20623078.82UniProt (P0A7V3)
Pfam (PF07650)
Pfam (PF00189)		Escherichia coli BW25113Small ribosomal subunit protein uS3
35IA, MC
(d, dd)		30S ribosomal protein S4polymer20523383.02UniProt (P0A7V8)
Pfam (PF00163)
Pfam (PF01479)		Escherichia coli BW25113Small ribosomal subunit protein uS4
36JA, NC
(e, ee)		30S ribosomal protein S5polymer15716532.12UniProt (P0A7W1)
Pfam (PF00333)
Pfam (PF03719)		Escherichia coli BW25113Small ribosomal subunit protein uS5
37KA, OC
(f, ff)		30S ribosomal protein S6polymer10011669.42UniProt (P02358)
Pfam (PF01250)		Escherichia coli BW25113Small ribosomal subunit protein bS6
38LA, PC
(g, gg)		30S ribosomal protein S7polymer16118048.92UniProt (P02359)
Pfam (PF00177)		Escherichia coli BW25113Small ribosomal subunit protein uS7
39MA, QC
(h, hh)		30S ribosomal protein S8polymer12914015.42UniProt (P0A7W7)
Pfam (PF00410)		Escherichia coli BW25113Small ribosomal subunit protein uS8
40NA, RC
(i, ii)		30S ribosomal protein S9polymer12714554.92UniProt (P0A7X3)
Pfam (PF00380)		Escherichia coli BW25113Small ribosomal subunit protein uS9
41OA, SC
(j, jj)		30S ribosomal protein S10polymer9811197.02UniProt (P0A7R5)
Pfam (PF00338)		Escherichia coli BW25113Small ribosomal subunit protein uS10
42PA, TC
(k, kk)		30S ribosomal protein S11polymer11612388.12UniProt (P0A7R9)
Pfam (PF00411)		Escherichia coli BW25113Small ribosomal subunit protein uS11
43QA, UC
(l, ll)		30S ribosomal protein S12polymer12313637.02UniProt (P0A7S3)
Pfam (PF00164)		Escherichia coli BW25113Small ribosomal subunit protein uS12
44RA, VC
(m, mm)		30S ribosomal protein S13polymer11412625.82UniProt (P0A7S9)
Pfam (PF00416)		Escherichia coli BW25113Small ribosomal subunit protein uS13
45SA, WC
(n, nn)		30S ribosomal protein S14polymer10111546.42UniProt (P0AG59)
Pfam (PF00253)		Escherichia coli BW25113Small ribosomal subunit protein uS14
46TA, XC
(o, oo)		30S ribosomal protein S15polymer8810159.62UniProt (P0ADZ4)
Pfam (PF00312)		Escherichia coli BW25113Small ribosomal subunit protein uS15
47UA, YC
(p, pp)		30S ribosomal protein S16polymer829207.62UniProt (P0A7T3)
Pfam (PF00886)		Escherichia coli BW25113Small ribosomal subunit protein bS16
48VA, ZC
(q, qq)		30S ribosomal protein S17polymer809263.92UniProt (P0AG63)
Pfam (PF00366)		Escherichia coli BW25113Small ribosomal subunit protein uS17
49AD, WA
(r, rr)		30S ribosomal protein S18polymer657606.82UniProt (P0A7T7)
Pfam (PF01084)		Escherichia coli BW25113Small ribosomal subunit protein bS18
50BD, XA
(s, ss)		30S ribosomal protein S19polymer799057.62UniProt (P0A7U3)
Pfam (PF00203)		Escherichia coli BW25113Small ribosomal subunit protein uS19
51CD, YA
(t, tt)		30S ribosomal protein S20polymer859506.22UniProt (P0A7U7)
Pfam (PF01649)		Escherichia coli BW25113Small ribosomal subunit protein bS20
52DD, ZA
(u, uu)		30S ribosomal protein S21polymer657763.12UniProt (P68679)
Pfam (PF01165)		Escherichia coli BW25113Small ribosomal subunit protein bS21
53AB, ED
(v, vv)		Ribosome modulation factorpolymer556520.52UniProt (P0AFW2)
Pfam (PF04957)		Escherichia coli BW25113RMF,Hibernation factor RMF,Protein E
54BB, FD
(x, xx)		Ribosome hibernation promoting factorpolymer9510768.22UniProt (P0AFX0)
Pfam (PF02482)		Escherichia coli BW25113HPF,Hibernation factor HPF
55CB, GD
(y, yy)		30S ribosomal protein S1polymer55761238.92UniProt (P0AG67)
Pfam (PF00575)		Escherichia coli BW25113Bacteriophage Q beta RNA-directed RNA polymerase subunit I,Small ribosomal subunit protein bS1
56DB, HD
(w, ww)		tRNA Mixturepolymer7724771.82GenBank (1063812051)Escherichia coli BW25113
Sequence modifications
A, AA: 1 - 2903 (GenBank: 1036415628)
PDBExternal DatabaseDetails
C 747U 1155325conflict
G 1847A 1156425conflict
A 2069G 1156647conflict
B, BB: 1 - 120 (GenBank: 1393501787)
PDBExternal DatabaseDetails
A 120U 3006612conflict
b, bb: 8 - 225 (UniProt: P0A7V0)
PDBExternal DatabaseDetails
Gln 226-expression tag
Asp 227-expression tag
Leu 228-expression tag
Ala 229-expression tag
Ser 230-expression tag
Gln 231-expression tag
Ala 232-expression tag
Glu 233-expression tag
g, gg: 1 - 161 (UniProt: P02359)
PDBExternal DatabaseDetails
Ala 154Arg 155conflict
Ala 161Phe 162conflict
n, nn: 1 - 101 (UniProt: P0AG59)
PDBExternal DatabaseDetails
Ala 35-insertion
x, xx: 1 - 95 (UniProt: P0AFX0)
PDBExternal DatabaseDetails
Asp 57Asn 57conflict
Leu 61Ile 61conflict
w, ww: 1 - 76 (GenBank: 1063812051)
PDBExternal DatabaseDetails
U 29G 3258805conflict
A 41C 3258793conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains112
Total formula weight4434579.6
All*Total formula weight4434579.6
*Water molecules are not included.

238582

PDB entries from 2025-07-09

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