6H46
Human KRAS in complex with darpin K13
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GTPase KRas | polymer | 169 | 19208.6 | 1 | UniProt (P01116) Pfam (PF00071) | Homo sapiens (Human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
| 2 | B (B) | darpin K13 | polymer | 156 | 16832.1 | 1 | Homo sapiens | ||
| 3 | C (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 4 | D, E (B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 224 | Chemie (HOH) |
Sequence modifications
A: 1 - 166 (UniProt: P01116)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Val 12 | Gly 12 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36040.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 635.3 | |
| All* | Total formula weight | 36676.0 |
