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6H2Z

The crystal structure of human carbonic anhydrase II in complex with 4-(4-phenylpiperidine-1-carbonyl)benzenesulfonamide.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Carbonic anhydrase 2polymer26229477.31UniProt (P00918)
Pfam (PF00194)
Homo sapiens (Human)Carbonate dehydratase II,Carbonic anhydrase C,CAC,Carbonic anhydrase II,CA-II
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
4-(4-phenylpiperidin-1-yl)carbonylbenzenesulfonamidenon-polymer344.41Chemie (FKE)
4D, E
(A)
GLYCEROLnon-polymer92.12Chemie (GOL)
5F
(A)
waterwater18.0158Chemie (HOH)
Sequence modifications
A: 1 - 261 (UniProt: P00918)
PDBExternal DatabaseDetails
Met -1-expression tag
Gly 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight29477.3
Non-Polymers*Number of molecules4
Total formula weight594.0
All*Total formula weight30071.3
*Water molecules are not included.

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PDB entries from 2025-06-18

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