6H2Y

human Fab 1E6 bound to fHbp variant 3 from Neisseria meningitidis serogroup B

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (D)	Lipoprotein GNA1870	polymer	275	29969.4	1	UniProt (Q19KF7) Pfam (PF20937) Pfam (PF08794)	Neisseria meningitidis
2	B (H)	Heavy chain	polymer	224	23559.4	1		Homo sapiens
3	C (L)	Light chain	polymer	216	23098.6	1		Homo sapiens
4	D, E, F, G, H... (H, L)	1,2-ETHANEDIOL	non-polymer		62.1	12	Chemie (EDO)
5	L (H)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
6	Q (L)	3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL	non-polymer		326.4	1	Chemie (P33)
7	R (L)	TETRAETHYLENE GLYCOL	non-polymer		194.2	1	Chemie (PG4)
8	S, T, U (D, H, L)	water	water		18.0	74	Chemie (HOH)

Sequence modifications

D: 12 - 261 (UniProt: Q19KF7)

PDB	External Database	Details
Met 0	-	initiating methionine
Gly 1	-	expression tag
Pro 2	-	expression tag
Asp 3	-	expression tag
Ser 4	-	expression tag
Asp 5	-	expression tag
Arg 6	-	expression tag
Leu 7	-	expression tag
Gln 8	-	expression tag
Gln 9	-	expression tag
Arg 10	-	expression tag
Arg 11	-	expression tag
Lys 262	-	expression tag
Leu 263	-	expression tag
Ala 264	-	expression tag
Ala 265	-	expression tag
Ala 266	-	expression tag
Leu 267	-	expression tag
Glu 268	-	expression tag
His 269	-	expression tag
His 270	-	expression tag
His 271	-	expression tag
His 272	-	expression tag
His 273	-	expression tag
His 274	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	76627.4
Non-Polymers*	Number of molecules	15
	Total formula weight	1371.5
All*	Total formula weight	77998.9

*Water molecules are not included.