6H2P
Crystal Structure of Arg184Gln mutant of Human Prolidase with Mn ions and Cacodylate ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Xaa-Pro dipeptidase | polymer | 492 | 54514.9 | 2 | UniProt (P12955) Pfam (PF05195) Pfam (PF00557) In PDB | Homo sapiens (Human) | X-Pro dipeptidase,Imidodipeptidase,Peptidase D,Proline dipeptidase,Prolidase |
| 2 | A, B | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
| 3 | A, B | CACODYLATE ION | non-polymer | 137.0 | 2 | Chemie (CAC) | |||
| 4 | A, B | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 1309 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 492 (UniProt: P12955)
| PDB | External Database | Details |
|---|---|---|
| Gln 184 | Arg 184 | engineered mutation |
| - | Ala 485 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 109029.8 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 954.2 | |
| All* | Total formula weight | 109984.0 |
