6H2I

Structure of BlaC from Mycobacterium tuberculosis bound to the trans-enamine adduct of tazobactam.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Beta-lactamase	polymer	274	29475.1	2	UniProt (A0A0T9EA39)	Mycobacterium tuberculosis
2	C, E (A, B)	TAZOBACTAM INTERMEDIATE	non-polymer		302.3	2	Chemie (TBE)
3	D, F (A, B)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
4	G, H (A, B)	water	water		18.0	6	Chemie (HOH)

Sequence modifications

A, B: 29 - 293 (UniProt: A0A0T9EA39)

PDB	External Database	Details
Met 28	-	initiating methionine
Leu 294	-	expression tag
Glu 295	-	expression tag
His 296	-	expression tag
His 297	-	expression tag
His 298	-	expression tag
His 299	-	expression tag
His 300	-	expression tag
His 301	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	58950.1
Non-Polymers*	Number of molecules	4
	Total formula weight	722.7
All*	Total formula weight	59672.8

*Water molecules are not included.