6H1H
Crystal structure of human Pirin in complex with compound 7 (PLX4720)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Pirin | polymer | 293 | 32441.7 | 1 | UniProt (O00625) Pfam (PF02678) Pfam (PF05726) In PDB | Homo sapiens (Human) | Probable quercetin 2,3-dioxygenase PIR,Probable quercetinase |
| 2 | A | FE (III) ION | non-polymer | 55.8 | 1 | Chemie (FE) | |||
| 3 | A | [3-azanyl-2,6-bis(fluoranyl)phenyl]-(5-chloranyl-1~{H}-pyrrolo[2,3-b]pyridin-3-yl)methanone | non-polymer | 307.7 | 1 | Chemie (FJE) | |||
| 4 | A | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 6 | water | water | 18.0 | 349 | Chemie (HOH) |
Sequence modifications
A: 1 - 290 (UniProt: O00625)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32441.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 763.9 | |
| All* | Total formula weight | 33205.6 |
