6H16
Structure of LRP6 P3E3P4E4 in complex with VHH L-P2-D07
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Low-density lipoprotein receptor-related protein 6 | polymer | 618 | 69880.7 | 1 | UniProt (O75581) Pfam (PF00058) Pfam (PF14670) | Homo sapiens (Human) | LRP-6 |
| 2 | B (B) | VHH L-P2-D07 | polymer | 119 | 13088.5 | 1 | Lama glama (Llama) | ||
| 3 | C, D, E (C, D, E) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 4 | F (F) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 5 | G (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 6 | H (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 7 | I (A) | water | water | 18.0 | 15 | Chemie (HOH) |
Sequence modifications
A: 630 - 1244 (UniProt: O75581)
| PDB | External Database | Details |
|---|---|---|
| Ala 1245 | - | expression tag |
| Ala 1246 | - | expression tag |
| Ala 1247 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 82969.3 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2508.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 261.3 | |
| All* | Total formula weight | 85738.8 |






