6H0W
Crystal Structure of KDM4D with tetrazolylhydrazide ligand NS035
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Lysine-specific demethylase 4D | polymer | 342 | 39491.8 | 1 | UniProt (Q6B0I6) Pfam (PF02375) Pfam (PF02373) | Homo sapiens (Human) | JmjC domain-containing histone demethylation protein 3D,Jumonji domain-containing protein 2D |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 4 | D, E, F, G, H... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 9 | Chemie (EDO) | |||
| 5 | M (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | N (A) | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) | |||
| 7 | O (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 8 | P (A) | (2~{R})-3-phenyl-2-(2~{H}-1,2,3,4-tetrazol-5-yl)propanehydrazide | non-polymer | 232.2 | 1 | Chemie (FHW) | |||
| 9 | Q (A) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 10 | R (A) | [2-(2~{H}-1,2,3,4-tetrazol-5-yl)ethanoylamino]azanium | non-polymer | 143.1 | 1 | Chemie (I1L) | |||
| 11 | S (A) | water | water | 18.0 | 458 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39491.8 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1450.9 | |
| All* | Total formula weight | 40942.7 |
