6H0V
Crystal structure of tabun surrogate NEDPA inhibited recombinant human bile salt activated lipase
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Bile salt-activated lipase | polymer | 547 | 60877.8 | 1 | UniProt (P19835) Pfam (PF00135) In PDB | Homo sapiens (Human) | BAL,Bile salt-stimulated lipase,BSSL,Bucelipase,Carboxyl ester lipase,Cholesterol esterase,Pancreatic lysophospholipase,Sterol esterase |
2 | A | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) | |||
3 | A | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
4 | water | water | 18.0 | 74 | Chemie (HOH) |
Sequence modifications
A: 2 - 533 (UniProt: P19835)
PDB | External Database | Details |
---|---|---|
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
Glu -5 | - | expression tag |
Asn -4 | - | expression tag |
Leu -3 | - | expression tag |
Tyr -2 | - | expression tag |
Phe -1 | - | expression tag |
Gln 0 | - | expression tag |
Ser 1 | - | expression tag |
Asp 186 | Asn 206 | engineered mutation |
Asp 298 | Ala 318 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 60877.8 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 563.2 | |
All* | Total formula weight | 61441.0 |