6GX1
Blood group synthase AAGlyB in complex with UDP-GalNAc and cryoprotected with PEG 3350
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase) | polymer | 298 | 34654.0 | 1 | UniProt (F0X360) Pfam (PF03414) UniProt (by SIFTS) (P16442) | Homo sapiens (Human) | |
| 2 | B (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) PubChem (27854) | |||
| 3 | C (A) | URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE | non-polymer | 607.4 | 1 | Chemie (UD2) | |||
| 4 | D (A) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 1 | Chemie (UDP) PubChem (1158) PubChem (6031) PubChem (25323044) PubChem (25323048) PubChem (44298965) PubChem (53486216) PubChem (3084486) PubChem (60098857) PubChem (57448939) PubChem (6101632) PubChem (6604175) PubChem (91746160) PubChem (92332560) PubChem (92332561) PubChem (92332562) PubChem (92332563) PubChem (11811538) PubChem (93088131) PubChem (93630083) PubChem (12049241) | |||
| 5 | E, F, G (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | H (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) PubChem (8117) | |||
| 7 | I (A) | water | water | 18.0 | 322 | Chemie (HOH) |
Sequence modifications
A: 64 - 354 (UniProt: F0X360)
| PDB | External Database | Details |
|---|---|---|
| Met 57 | - | initiating methionine |
| Ala 58 | - | expression tag |
| Ile 59 | - | expression tag |
| Gly 60 | - | expression tag |
| Glu 61 | - | expression tag |
| Phe 62 | - | expression tag |
| Met 63 | - | expression tag |
| Gly 266 | Leu 256 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34654.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1460.8 | |
| All* | Total formula weight | 36114.8 |
