6GVK
Second pair of Fibronectin type III domains of integrin beta4 (T1663R mutant) bound to the bullous pemphigoid antigen BP230 (BPAG1e)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Integrin beta-4 | polymer | 214 | 23438.3 | 1 | UniProt (P16144) Pfam (PF00041) | Homo sapiens (Human) | GP150 |
| 2 | B (B) | Dystonin | polymer | 30 | 3208.5 | 1 | UniProt (Q03001) | Homo sapiens | 230 kDa bullous pemphigoid antigen,230/240 kDa bullous pemphigoid antigen,Bullous pemphigoid antigen 1,Bullous pemphigoid antigen,Dystonia musculorum protein,Hemidesmosomal plaque protein |
| 3 | C, D (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 105 | Chemie (HOH) |
Sequence modifications
A: 1457 - 1666 (UniProt: P16144)
| PDB | External Database | Details |
|---|---|---|
| Gly 1453 | - | expression tag |
| Ser 1454 | - | expression tag |
| His 1455 | - | expression tag |
| Met 1456 | - | expression tag |
| Arg 1663 | Thr 1733 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 26646.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 184.2 | |
| All* | Total formula weight | 26831.0 |
