6GVK

Second pair of Fibronectin type III domains of integrin beta4 (T1663R mutant) bound to the bullous pemphigoid antigen BP230 (BPAG1e)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Integrin beta-4	polymer	214	23438.3	1	UniProt (P16144) Pfam (PF00041) In PDB	Homo sapiens (Human)	GP150
2	B	Dystonin	polymer	30	3208.5	1	UniProt (Q03001) In PDB	Homo sapiens	230 kDa bullous pemphigoid antigen,230/240 kDa bullous pemphigoid antigen,Bullous pemphigoid antigen 1,Bullous pemphigoid antigen,Dystonia musculorum protein,Hemidesmosomal plaque protein
3	A	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4		water	water		18.0	105	Chemie (HOH)

Sequence modifications

A: 1457 - 1666 (UniProt: P16144)

PDB	External Database	Details
Gly 1453	-	expression tag
Ser 1454	-	expression tag
His 1455	-	expression tag
Met 1456	-	expression tag
Arg 1663	Thr 1733	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	26646.8
Non-Polymers*	Number of molecules	2
	Total formula weight	184.2
All*	Total formula weight	26831.0

*Water molecules are not included.