6GUF
CDK2/CyclinA in complex with CGP74514A
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Cyclin-dependent kinase 2 | polymer | 302 | 34354.8 | 2 | UniProt (P24941) Pfam (PF00069) In PDB | Homo sapiens (Human) | Cell division protein kinase 2,p33 protein kinase |
2 | B, D | Cyclin-A2 | polymer | 268 | 30817.5 | 2 | UniProt (P30274) Pfam (PF00134) Pfam (PF02984) In PDB | Bos taurus (cattle) | Cyclin-A |
3 | A, C | N2-[(1R,2S)-2-AMINOCYCLOHEXYL]-N6-(3-CHLOROPHENYL)-9-ETHYL-9H-PURINE-2,6-DIAMINE | non-polymer | 385.9 | 2 | Chemie (23D) | |||
4 | water | water | 18.0 | 124 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 298 (UniProt: P24941)
B, D: 172 - 432 (UniProt: P30274)
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Pro -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 171 | - | expression tag |
His 433 | - | expression tag |
His 434 | - | expression tag |
His 435 | - | expression tag |
His 436 | - | expression tag |
His 437 | - | expression tag |
His 438 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 130344.5 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 771.8 | |
All* | Total formula weight | 131116.3 |