6GS6
Cyclophilin A single mutant D66A in complex with an inhibitor.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peptidyl-prolyl cis-trans isomerase A | polymer | 165 | 17992.5 | 1 | UniProt (P62937) Pfam (PF00160) | Homo sapiens (Human) | PPIase A,Cyclophilin A,Cyclosporin A-binding protein,Rotamase A |
| 2 | B (A) | ethyl N-[(4-aminobenzyl)carbamoyl]glycinate | non-polymer | 251.3 | 1 | Chemie (EA4) | |||
| 3 | C (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | D (A) | water | water | 18.0 | 194 | Chemie (HOH) |
Sequence modifications
A: 1 - 165 (UniProt: P62937)
| PDB | External Database | Details |
|---|---|---|
| Ala 66 | Asp 66 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17992.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 329.4 | |
| All* | Total formula weight | 18321.9 |
