6GRA
Human AURKA bound to BRD-7880
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Aurora kinase A | polymer | 285 | 32948.8 | 1 | UniProt (O14965) Pfam (PF00069) In PDB | Homo sapiens (Human) | Aurora 2,Aurora/IPL1-related kinase 1,hARK1,Breast tumor-amplified kinase,Serine/threonine-protein kinase 15,Serine/threonine-protein kinase 6,Serine/threonine-protein kinase aurora-A |
2 | A | 1-[(2~{R},3~{S})-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-3-methyl-6-oxidanylidene-5-[(2~{S})-1-oxidanylpropan-2-yl]-3,4-dihydro-2~{H}-1,5-benzoxazocin-8-yl]-3-(4-methoxyphenyl)urea | non-polymer | 590.7 | 1 | Chemie (F8Z) | |||
3 | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A: 122 - 403 (UniProt: O14965)
PDB | External Database | Details |
---|---|---|
Gly 119 | - | expression tag |
Ala 120 | - | expression tag |
Met 121 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 32948.8 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 590.7 | |
All* | Total formula weight | 33539.4 |