6GQW
KRAS-169 Q61H GPPNHP + CH-1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, F | GTPase KRas | polymer | 171 | 19519.0 | 5 | UniProt (P01116) Pfam (PF00071) In PDB | Homo sapiens (Human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
2 | E | GTPase KRas | polymer | 171 | 19517.0 | 1 | UniProt (P01116) Pfam (PF00071) In PDB | Homo sapiens (Human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
3 | A, B, C, D, E... | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
4 | A, B, C, D, E... | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 6 | Chemie (GNP) | |||
5 | A, B, C, F | [4-[[4-(3-methoxyphenyl)phenyl]amino]phenyl]methyl-dimethyl-azanium | non-polymer | 333.4 | 4 | Chemie (F8T) | |||
6 | water | water | 18.0 | 36 | Chemie (HOH) |
Sequence modifications
A, B, C, D, F: 1 - 167 (UniProt: P01116)
E: 1 - 167 (UniProt: P01116)
PDB | External Database | Details |
---|---|---|
Tyr -3 | - | expression tag |
Phe -2 | - | expression tag |
Gln -1 | - | expression tag |
Gly 0 | - | expression tag |
His 61 | Gln 61 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Tyr -3 | - | expression tag |
Phe -2 | - | expression tag |
Gln -1 | - | expression tag |
Gly 0 | - | expression tag |
Val 20 | Thr 20 | conflict |
His 61 | Gln 61 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 117112.1 | |
Non-Polymers* | Number of molecules | 16 |
Total formula weight | 4612.8 | |
All* | Total formula weight | 121724.9 |