6GQW

KRAS-169 Q61H GPPNHP + CH-1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, F (A, B, C, D, F)	GTPase KRas	polymer	171	19519.0	5	UniProt (P01116) Pfam (PF00071)	Homo sapiens (Human)	K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras
2	E (E)	GTPase KRas	polymer	171	19517.0	1	UniProt (P01116) Pfam (PF00071)	Homo sapiens (Human)	K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras
3	G, J, M, P, R... (A, B, C, D, E...)	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
4	H, K, N, Q, S... (A, B, C, D, E...)	PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER	non-polymer		522.2	6	Chemie (GNP)
5	I, L, O, V (A, B, C, F)	[4-[[4-(3-methoxyphenyl)phenyl]amino]phenyl]methyl-dimethyl-azanium	non-polymer		333.4	4	Chemie (F8T)
6	AA, BA, W, X, Y... (E, F, A, B, C...)	water	water		18.0	36	Chemie (HOH)

Sequence modifications

A, B, C, D, F: 1 - 167 (UniProt: P01116)

PDB	External Database	Details
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag
His 61	Gln 61	engineered mutation

E: 1 - 167 (UniProt: P01116)

PDB	External Database	Details
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag
Val 20	Thr 20	conflict
His 61	Gln 61	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	117112.1
Non-Polymers*	Number of molecules	16
	Total formula weight	4612.8
All*	Total formula weight	121724.9

*Water molecules are not included.