6GQT
KRAS-169 Q61H GPPNHP + PPIN-2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | GTPase KRas | polymer | 171 | 19485.0 | 6 | UniProt (P01116) Pfam (PF00071) | Homo sapiens (Human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
| 2 | G, K, N, Q, U... (A, B, C, D, E...) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 6 | Chemie (GNP) | |||
| 3 | H, L, O, R, V... (A, B, C, D, E...) | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
| 4 | I, J, T (A, D) | CITRIC ACID | non-polymer | 192.1 | 3 | Chemie (CIT) | |||
| 5 | M, P, S, Y (B, C, D, F) | ~{N}-(3-imidazol-1-ylpropyl)-4-[[3-(3-methoxyphenyl)phenyl]methyl]oxane-4-carboxamide | non-polymer | 433.5 | 4 | Chemie (F8N) | |||
| 6 | AA, BA, CA, DA, EA... (B, C, D, E, F...) | water | water | 18.0 | 686 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 168 (UniProt: P01116)
| PDB | External Database | Details |
|---|---|---|
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
| Gly 0 | - | expression tag |
| His 61 | Gln 61 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 116909.7 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 5589.6 | |
| All* | Total formula weight | 122499.3 |
