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6GQ3

Human asparagine synthetase (ASNS) in complex with 6-diazo-5-oxo-L-norleucine (DON) at 1.85 A resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Asparagine synthetase [glutamine-hydrolyzing]polymer56164455.82UniProt (P08243)
Pfam (PF13537)
Pfam (PF00733)
Homo sapiens (Human)Cell cycle control protein TS11,Glutamine-dependent asparagine synthetase
2C, I
(A, B)
5-OXO-L-NORLEUCINEnon-polymer145.22Chemie (ONL)
3D, E, F, J
(A, B)
1,2-ETHANEDIOLnon-polymer62.14Chemie (EDO)
4G, K
(A, B)
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACIDnon-polymer238.32Chemie (EPE)
5H, L
(A, B)
CHLORIDE IONnon-polymer35.52Chemie (CL)
6M, N
(A, B)
waterwater18.0568Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight128911.6
Non-Polymers*Number of molecules10
Total formula weight1086.1
All*Total formula weight129997.7
*Water molecules are not included.

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PDB entries from 2025-06-18

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