6GNR

Crystal Structure Of Sea Bream Transthyretin in complex with 2-(3-chloro-2-methylanilino)pyridine-3-carboxylic acid (Clonixin)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Transthyretin	polymer	135	14455.1	2	UniProt (Q9PTT3) Pfam (PF00576)	Sparus aurata (Gilthead seabream)
2	C, D (A, B)	2-(3-chloro-2-methylanilino)pyridine-3-carboxylic acid	non-polymer		262.7	2	Chemie (6J3)
3	E, F (A, B)	water	water		18.0	362	Chemie (HOH)

Sequence modifications

A, B: -4 - 125 (UniProt: Q9PTT3)

PDB	External Database	Details
Gly -7	-	expression tag
Ala -6	-	expression tag
Met -5	-	expression tag
His 126	-	expression tag
Glu 127	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	28910.2
Non-Polymers*	Number of molecules	2
	Total formula weight	525.4
All*	Total formula weight	29435.6

*Water molecules are not included.