6GN1
Crystal Structure of Glycogen synthase kinase-3 beta (GSK3B) in Complex with PIK-75
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Glycogen synthase kinase-3 beta | polymer | 368 | 41670.7 | 2 | UniProt (P49841) Pfam (PF00069) | Homo sapiens (Human) | GSK-3 beta,Serine/threonine-protein kinase GSK3B |
| 2 | C, E (B, A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 3 | D, F (B, A) | ~{N}-[(~{E})-(6-bromanylimidazo[1,2-a]pyridin-3-yl)methylideneamino]-~{N},2-dimethyl-5-nitro-benzenesulfonamide | non-polymer | 452.3 | 2 | Chemie (F4N) | |||
| 4 | G, H (B, A) | water | water | 18.0 | 109 | Chemie (HOH) |
Sequence modifications
B, A: 27 - 393 (UniProt: P49841)
| PDB | External Database | Details |
|---|---|---|
| Gly 26 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 83341.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 975.5 | |
| All* | Total formula weight | 84316.8 |
