6GL3
Crystal structure of human Phosphatidylinositol 4-kinase III beta (PI4KIIIbeta) in complex with ligand 44
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Phosphatidylinositol 4-kinase beta,Phosphatidylinositol 4-kinase beta | polymer | 386 | 43988.7 | 2 | UniProt (Q9UBF8) Pfam (PF00454) | Homo sapiens (Human) | PtdIns 4-kinase beta,NPIK,PI4K92,PtdIns 4-kinase beta,NPIK,PI4K92 |
| 2 | C (A) | (3~{S})-4-(6-azanyl-1-methyl-pyrazolo[3,4-d]pyrimidin-4-yl)-~{N}-(4-methoxy-2-methyl-phenyl)-3-methyl-piperazine-1-carboxamide | non-polymer | 410.5 | 1 | Chemie (EMW) | |||
| 3 | D (A) | water | water | 18.0 | 15 | Chemie (HOH) |
Sequence modifications
A, B: 317 - 525 (UniProt: Q9UBF8)
A, B: 532 - 798 (UniProt: Q9UBF8)
| PDB | External Database | Details |
|---|---|---|
| Gly 316 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Asp 526 | - | linker |
| Ser 527 | - | linker |
| Gly 528 | - | linker |
| Asp 529 | - | linker |
| Gly 530 | - | linker |
| Ser 531 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 87977.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 410.5 | |
| All* | Total formula weight | 88387.9 |
