6GKL

Translation initiation factor 4E in complex with beta-phosphorothioate trinucleotide mRNA 5' cap diastereomer 2 (m7GppSpApG D2)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Eukaryotic translation initiation factor 4E	polymer	190	22145.1	4	UniProt (P63073) Pfam (PF01652) In PDB	Mus musculus (Mouse)	mRNA cap-binding protein,eIF-4F 25 kDa subunit
2	A, B, C, D	[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-azanyl-4,5-dihydropurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-sulfanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate	non-polymer		1135.7	4	Chemie (G0Z)
3	A, B	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4		water	water		18.0	190	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	88580.5
Non-Polymers*	Number of molecules	6
	Total formula weight	4727.1
All*	Total formula weight	93307.6

*Water molecules are not included.