6GHA

USP15 catalytic domain structure

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Ubiquitin carboxyl-terminal hydrolase 15,Ubiquitin carboxyl-terminal hydrolase 15	polymer	365	41747.2	1	UniProt (Q9Y4E8) Pfam (PF00443)	Homo sapiens (Human)	Deubiquitinating enzyme 15,Ubiquitin thioesterase 15,Ubiquitin-specific-processing protease 15,Unph-2,Unph4,Deubiquitinating enzyme 15,Ubiquitin thioesterase 15,Ubiquitin-specific-processing protease 15,Unph-2,Unph4
2	B (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
3	C (A)	water	water		18.0	131	Chemie (HOH)

Sequence modifications

A: 255 - 439 (UniProt: Q9Y4E8)

PDB	External Database	Details
Met 254	-	initiating methionine

A: 757 - 919 (UniProt: Q9Y4E8)

PDB	External Database	Details
Ala 440	-	linker
Ser 753	-	linker
Thr 754	-	linker
Ser 755	-	linker
Lys 756	-	linker
Ala 920	-	expression tag
Ala 921	-	expression tag
Ala 922	-	expression tag
Leu 923	-	expression tag
Glu 924	-	expression tag
His 925	-	expression tag
His 926	-	expression tag
His 927	-	expression tag
His 928	-	expression tag
His 929	-	expression tag
His 930	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	41747.2
Non-Polymers*	Number of molecules	1
	Total formula weight	65.4
All*	Total formula weight	41812.6

*Water molecules are not included.