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6GEE

TEAD4 (216-434);E263A COMPLEXED WITH YAP PEPTIDE (60-100); S94A AND MYRISTOATE (COVALENTLY BOUND) AT 1.96A (P41212 CRYSTAL FORM); MYRISTOYLATION WAS DONE BY ADDING MYR-COA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ATranscriptional enhancer factor TEF-3polymer21925442.71UniProt (Q15561)
Pfam (PF17725)
In PDB
Homo sapiens (Human)TEA domain family member 4,TEAD-4,Transcription factor 13-like 1,Transcription factor RTEF-1
2LTranscriptional coactivator YAP1polymer414531.21UniProt (P46937)
In PDB
Homo sapiensYes-associated protein 1,Protein yorkie homolog,Yes-associated protein YAP65 homolog
3AMYRISTIC ACIDnon-polymer228.41Chemie (MYR)
4waterwater18.0223Chemie (HOH)
Sequence modifications
A: 216 - 434 (UniProt: Q15561)
PDBExternal DatabaseDetails
Ala 263Glu 263engineered mutation
L: 60 - 99 (UniProt: P46937)
PDBExternal DatabaseDetails
Ace 59-expression tag
Ala 94Ser 94engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight29973.9
Non-Polymers*Number of molecules1
Total formula weight228.4
All*Total formula weight30202.3
*Water molecules are not included.

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PDB entries from 2024-06-12

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