6GCX
Focal Adhesion Kinase catalytic domain in complex with irreversible inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Focal adhesion kinase 1 | polymer | 276 | 31731.8 | 1 | UniProt (Q00944) Pfam (PF07714) | Gallus gallus (Chicken) | FADK 1,Focal adhesion kinase-related nonkinase,p41/p43FRNK,Protein-tyrosine kinase 2,p125FAK,pp125FAK |
| 2 | B (A) | 2-[[2-[[4-[[[3,4-bis(oxidanylidene)-2-[2-(propanoylamino)ethylamino]cyclobuten-1-yl]amino]methyl]phenyl]amino]-5-chloranyl-pyrimidin-4-yl]amino]-~{N}-methyl-benzamide | non-polymer | 577.0 | 1 | Chemie (EUW) | |||
| 3 | C, D (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | E (A) | water | water | 18.0 | 182 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31731.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 769.2 | |
| All* | Total formula weight | 32501.0 |
