6G8R
SP140 PHD-Bromodomain complex with scFv
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | single-chain variable fragment | polymer | 250 | 26590.3 | 1 | Homo sapiens (Human) | ||
| 2 | B (B) | Nuclear body protein SP140 | polymer | 198 | 23512.8 | 1 | UniProt (Q13342) Pfam (PF00628) Pfam (PF00439) | Homo sapiens (Human) | Lymphoid-restricted homolog of Sp100,LYSp100,Nuclear autoantigen Sp-140,Speckled 140 kDa |
| 3 | C, D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | E, F (B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | G, H (A, B) | water | water | 18.0 | 13 | Chemie (HOH) |
Sequence modifications
B: 687 - 862 (UniProt: Q13342)
| PDB | External Database | Details |
|---|---|---|
| Ser 686 | - | expression tag |
| Ser 863 | - | expression tag |
| Ser 864 | - | expression tag |
| Lys 865 | - | expression tag |
| Gly 866 | - | expression tag |
| Gly 867 | - | expression tag |
| Tyr 868 | - | expression tag |
| Gly 869 | - | expression tag |
| Leu 870 | - | expression tag |
| Asn 871 | - | expression tag |
| Asp 872 | - | expression tag |
| Ile 873 | - | expression tag |
| Phe 874 | - | expression tag |
| Glu 875 | - | expression tag |
| Ala 876 | - | expression tag |
| Gln 877 | - | expression tag |
| Lys 878 | - | expression tag |
| Ile 879 | - | expression tag |
| Glu 880 | - | expression tag |
| Trp 881 | - | expression tag |
| His 882 | - | expression tag |
| Glu 883 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 50103.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 255.0 | |
| All* | Total formula weight | 50358.1 |
