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6G8Q

14-3-3sigma in complex with a A130beta3A and Q133beta3Q mutated YAP pS127 phosphopeptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
14-3-3 protein sigmapolymer23626542.91UniProt (P31947)
Pfam (PF00244)
Homo sapiens (Human)Epithelial cell marker protein 1,Stratifin
2B
(P)
Transcriptional coactivator YAP1polymer111189.21UniProt (P46937)Homo sapiensYes-associated protein 1,Protein yorkie homolog,Yes-associated protein YAP65 homolog
3C
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
4D, E
(A)
CHLORIDE IONnon-polymer35.52Chemie (CL)
5F, G, H
(A)
SODIUM IONnon-polymer23.03Chemie (NA)
6I, J
(A, P)
waterwater18.0357Chemie (HOH)
Sequence modifications
A: 1 - 231 (UniProt: P31947)
PDBExternal DatabaseDetails
Gly -4-expression tag
Ala -3-expression tag
Met -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
P: 124 - 133 (UniProt: P46937)
PDBExternal DatabaseDetails
Ace 123-acetylation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight27732.1
Non-Polymers*Number of molecules6
Total formula weight180.0
All*Total formula weight27912.1
*Water molecules are not included.

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PDB entries from 2025-06-18

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