6G5X
Crystal Structure of KDM4A with compound YP-02-145
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Lysine-specific demethylase 4A | polymer | 359 | 41767.5 | 2 | UniProt (O75164) Pfam (PF02375) Pfam (PF02373) | Homo sapiens (Human) | JmjC domain-containing histone demethylation protein 3A,Jumonji domain-containing protein 2A |
| 2 | C, L (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, E, F, M (A, B) | NICKEL (II) ION | non-polymer | 58.7 | 4 | Chemie (NI) | |||
| 4 | G, H, N, O (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 5 | I, J, P (A, B) | CITRIC ACID | non-polymer | 192.1 | 3 | Chemie (CIT) | |||
| 6 | K (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | Q (B) | 2-(3-methyl-5-oxidanylidene-4-phenyl-4~{H}-pyrazol-1-yl)-3~{H}-benzimidazole-5-carboxylic acid | non-polymer | 334.3 | 1 | Chemie (MY7) | |||
| 8 | R, S (A, B) | water | water | 18.0 | 551 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 83535.1 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1616.7 | |
| All* | Total formula weight | 85151.7 |
