6G5H
Cryo-EM structure of a late human pre-40S ribosomal subunit - Mature
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | 2 | 18S ribosomal RNA | polymer | 1868 | 602432.6 | 1 | GenBank (337376) | Homo sapiens | |
2 | A | 40S ribosomal protein SA | polymer | 295 | 32883.9 | 1 | UniProt (P08865) Pfam (PF00318) Pfam (PF16122) In PDB | Homo sapiens (Human) | 37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Colon carcinoma laminin-binding protein,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40,Multidrug resistance-associated protein MGr1-Ag,NEM/1CHD4,Small ribosomal subunit protein uS2 |
3 | B | 40S ribosomal protein S3a | polymer | 264 | 30002.1 | 1 | UniProt (P61247) Pfam (PF01015) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein eS1,v-fos transformation effector protein,Fte-1 |
4 | C | 40S ribosomal protein S2 | polymer | 293 | 31376.5 | 1 | UniProt (P15880) Pfam (PF00333) Pfam (PF03719) In PDB | Homo sapiens (Human) | 40S ribosomal protein S4,Protein LLRep3,Small ribosomal subunit protein uS5 |
5 | E | 40S ribosomal protein S4, X isoform | polymer | 263 | 29654.9 | 1 | UniProt (P62701) Pfam (PF00900) Pfam (PF00467) Pfam (PF16121) Pfam (PF08071) In PDB | Homo sapiens (Human) | SCR10,Single copy abundant mRNA protein,Small ribosomal subunit protein eS4 |
6 | G | 40S ribosomal protein S6 | polymer | 249 | 28751.9 | 1 | UniProt (P62753) Pfam (PF01092) In PDB | Homo sapiens (Human) | Phosphoprotein NP33,Small ribosomal subunit protein eS6 |
7 | H | 40S ribosomal protein S7 | polymer | 194 | 22168.9 | 1 | UniProt (P62081) Pfam (PF01251) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein eS7 |
8 | I | 40S ribosomal protein S8 | polymer | 208 | 24263.4 | 1 | UniProt (P62241) Pfam (PF01201) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein eS8 |
9 | J | 40S ribosomal protein S9 | polymer | 194 | 22641.6 | 1 | UniProt (P46781) Pfam (PF00163) Pfam (PF01479) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein uS4 |
10 | L | 40S ribosomal protein S11 | polymer | 158 | 18468.8 | 1 | UniProt (P62280) Pfam (PF16205) Pfam (PF00366) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein uS17 |
11 | N | 40S ribosomal protein S13 | polymer | 151 | 17259.4 | 1 | UniProt (P62277) Pfam (PF08069) Pfam (PF00312) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein uS15 |
12 | O | 40S ribosomal protein S14 | polymer | 151 | 16302.8 | 1 | UniProt (P62263) Pfam (PF00411) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein uS11 |
13 | V | 40S ribosomal protein S21 | polymer | 83 | 9124.4 | 1 | UniProt (P63220) Pfam (PF01249) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein eS21 |
14 | W | 40S ribosomal protein S15a | polymer | 130 | 14865.6 | 1 | UniProt (P62244) Pfam (PF00410) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein uS8 |
15 | X | 40S ribosomal protein S23 | polymer | 143 | 15844.7 | 1 | UniProt (P62266) Pfam (PF00164) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein uS12 |
16 | Y | 40S ribosomal protein S24 | polymer | 133 | 15463.3 | 1 | UniProt (P62847) Pfam (PF01282) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein eS24 |
17 | a | 40S ribosomal protein S26 | polymer | 115 | 13047.5 | 1 | UniProt (P62854) Pfam (PF01283) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein eS26 |
18 | b | 40S ribosomal protein S27 | polymer | 84 | 9480.2 | 1 | UniProt (P42677) Pfam (PF01667) In PDB | Homo sapiens (Human) | Metallopan-stimulin 1,MPS-1,Small ribosomal subunit protein eS27 |
19 | d | 40S ribosomal protein S29 | polymer | 56 | 6690.8 | 1 | UniProt (P62273) Pfam (PF00253) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein uS14 |
20 | e | 40S ribosomal protein S30 | polymer | 59 | 6668.9 | 1 | UniProt (P62861) Pfam (PF04758) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein eS30 |
21 | h | 60S ribosomal protein L41 | polymer | 25 | 3473.5 | 1 | UniProt (P62945) Pfam (PF05162) In PDB | Homo sapiens (Human) | HG12,Large ribosomal subunit protein eL41 |
22 | D | 40S ribosomal protein S3 | polymer | 243 | 26729.4 | 1 | UniProt (P23396) Pfam (PF07650) Pfam (PF00189) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein uS3 |
23 | F | 40S ribosomal protein S5 | polymer | 204 | 22913.5 | 1 | UniProt (P46782) Pfam (PF00177) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein uS7 |
24 | K | 40S ribosomal protein S10 | polymer | 165 | 18933.8 | 1 | UniProt (P46783) Pfam (PF03501) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein eS10 |
25 | M | 40S ribosomal protein S12 | polymer | 132 | 14539.0 | 1 | UniProt (P25398) Pfam (PF01248) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein eS12 |
26 | P | 40S ribosomal protein S15 | polymer | 145 | 17076.2 | 1 | UniProt (P62841) Pfam (PF00203) In PDB | Homo sapiens (Human) | RIG protein,Small ribosomal subunit protein uS19 |
27 | Q | 40S ribosomal protein S16 | polymer | 146 | 16477.4 | 1 | UniProt (P62249) Pfam (PF00380) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein uS9 |
28 | R | 40S ribosomal protein S17 | polymer | 135 | 15578.2 | 1 | UniProt (P08708) Pfam (PF00833) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein eS17 |
29 | S | 40S ribosomal protein S18 | polymer | 152 | 17759.8 | 1 | UniProt (P62269) Pfam (PF00416) In PDB | Homo sapiens (Human) | Ke-3,Ke3,Small ribosomal subunit protein uS13 |
30 | T | 40S ribosomal protein S19 | polymer | 145 | 16091.6 | 1 | UniProt (P39019) Pfam (PF01090) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein eS19 |
31 | U | 40S ribosomal protein S20 | polymer | 119 | 13398.8 | 1 | UniProt (P60866) Pfam (PF00338) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein uS10 |
32 | Z | 40S ribosomal protein S25 | polymer | 125 | 13776.2 | 1 | UniProt (P62851) Pfam (PF03297) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein eS25 |
33 | c | 40S ribosomal protein S28 | polymer | 69 | 7855.1 | 1 | UniProt (P62857) Pfam (PF01200) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein eS28 |
34 | f | Ribosomal protein S27a | polymer | 156 | 17944.0 | 1 | UniProt (Q5RKT7) Pfam (PF00240) Pfam (PF01599) UniProt (by SIFTS) (P62979) In PDB | Homo sapiens (Human) | |
35 | g | Receptor of activated protein C kinase 1 | polymer | 317 | 35115.7 | 1 | UniProt (P63244) Pfam (PF00400) In PDB | Homo sapiens (Human) | Cell proliferation-inducing gene 21 protein,Guanine nucleotide-binding protein subunit beta-2-like 1,Guanine nucleotide-binding protein subunit beta-like protein 12.3,Human lung cancer oncogene 7 protein,HLC-7,Receptor for activated C kinase,Small ribosomal subunit protein RACK1 |
36 | a, d, f | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) |
Sequence modifications
2: 1 - 1869 (GenBank: 337376)
PDB | External Database | Details |
---|---|---|
C 1772 | G 1872 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 35 |
Total formula weight | 1225054.1 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 196.2 | |
All* | Total formula weight | 1225250.3 |