6G4Z
Crystal structure of murine NF-kappaB inducing kinase (NIK) in complex with compound 2f
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Mitogen-activated protein kinase kinase kinase 14 | polymer | 349 | 38543.4 | 2 | UniProt (Q9WUL6) Pfam (PF00069) | Mus musculus (Mouse) | NF-kappa-beta-inducing kinase,Serine/threonine-protein kinase NIK |
| 2 | C, D (A, B) | 5-fluoranyl-1-[4-[2-[(3~{R})-1-methyl-3-oxidanyl-2-oxidanylidene-pyrrol-3-yl]ethynyl]pyridin-2-yl]indazole-3-carboxamide | non-polymer | 391.4 | 2 | Chemie (ELW) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 18 | Chemie (HOH) |
Sequence modifications
A, B: 329 - 675 (UniProt: Q9WUL6)
| PDB | External Database | Details |
|---|---|---|
| Gly 327 | - | expression tag |
| Ser 328 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 77086.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 782.7 | |
| All* | Total formula weight | 77869.6 |
