6G4Y
Crystal structure of murine NF-kappaB inducing kinase (NIK) in complex with compound 1a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Mitogen-activated protein kinase kinase kinase 14 | polymer | 349 | 38543.4 | 2 | UniProt (Q9WUL6) Pfam (PF00069) | Mus musculus (House Mouse) | NF-kappa-beta-inducing kinase,Serine/threonine-protein kinase NIK |
| 2 | C, D, F, G (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | E, H (A, B) | 10-[2-[(3~{R})-1-methyl-3-oxidanyl-2-oxidanylidene-pyrrolidin-3-yl]ethynyl]-~{N}3-(oxan-4-yl)-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepine-2,3-dicarboxamide | non-polymer | 493.5 | 2 | Chemie (ELZ) | |||
| 4 | I, J (A, B) | water | water | 18.0 | 83 | Chemie (HOH) |
Sequence modifications
A, B: 329 - 675 (UniProt: Q9WUL6)
| PDB | External Database | Details |
|---|---|---|
| Gly 327 | - | expression tag |
| Ser 328 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 77086.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1371.3 | |
| All* | Total formula weight | 78458.2 |
