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6G4T

The crystal structure of uninhibited C183S/C217S mutant of human CA VII

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Carbonic anhydrase 7polymer27430925.71UniProt (P43166)
Pfam (PF00194)
Homo sapiens (Human)Carbonate dehydratase VII,Carbonic anhydrase VII,CA-VII
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
waterwater18.0162Chemie (HOH)
Sequence modifications
A: -1 - 262 (UniProt: P43166)
PDBExternal DatabaseDetails
Met -3-initiating methionine
Gly -2-expression tag
Ser 183Cys 185engineered mutation
Ser 217Cys 219engineered mutation
Leu 263-expression tag
Glu 264-expression tag
His 265-expression tag
His 266-expression tag
His 267-expression tag
His 268-expression tag
His 269-expression tag
His 270-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight30925.7
Non-Polymers*Number of molecules1
Total formula weight65.4
All*Total formula weight30991.1
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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