6G33
Crystal structure of CLK1 in complex with 5-iodotubercidin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dual specificity protein kinase CLK1 | polymer | 339 | 39741.5 | 1 | UniProt (P49759) Pfam (PF00069) | Homo sapiens (Human) | CDC-like kinase 1 |
| 2 | B, C (B, C) | Dual specificity protein kinase CLK1 | polymer | 339 | 39581.5 | 2 | UniProt (P49759) Pfam (PF00069) | Homo sapiens (Human) | CDC-like kinase 1 |
| 3 | D, G, I (A, B, C) | (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL | non-polymer | 392.1 | 3 | Chemie (5ID) | |||
| 4 | E, H, J (A, B, C) | IODIDE ION | non-polymer | 126.9 | 3 | Chemie (IOD) | |||
| 5 | F (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 6 | K, L, M (A, B, C) | water | water | 18.0 | 341 | Chemie (HOH) |
Sequence modifications
A: 148 - 484 (UniProt: P49759)
B, C: 148 - 484 (UniProt: P49759)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Met 0 | - | expression tag |
| Ala 432 | Arg 432 | variant |
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Met 0 | - | expression tag |
| Ala 432 | Arg 432 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 118904.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1652.1 | |
| All* | Total formula weight | 120556.6 |
