6G2Q
Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CHCL (S-isomer), beta, gamma dTTP analogue
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | T | Template Strand | polymer | 16 | 4853.2 | 1 | Homo sapiens | ||
2 | P | Primer Strand | polymer | 10 | 3045.0 | 1 | Homo sapiens | ||
3 | D | Downstream Primer Strand | polymer | 5 | 1536.0 | 1 | Homo sapiens | ||
4 | A | DNA polymerase beta | polymer | 335 | 38241.7 | 1 | UniProt (P06746) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) In PDB | Homo sapiens (Human) | |
5 | P, A | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
6 | A | [(~{S})-chloranyl-[[[(2~{R},3~{S},5~{R})-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]methyl]phosphonic acid | non-polymer | 514.6 | 1 | Chemie (EJH) | |||
7 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
8 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
9 | water | water | 18.0 | 161 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 47675.9 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 643.4 | |
All* | Total formula weight | 48319.2 |