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6G2Q

Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CHCL (S-isomer), beta, gamma dTTP analogue

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(T)
Template Strandpolymer164853.21Homo sapiens
2B
(P)
Primer Strandpolymer103045.01Homo sapiens
3C
(D)
Downstream Primer Strandpolymer51536.01Homo sapiens
4D
(A)
DNA polymerase betapolymer33538241.71UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (Human)
5E, I, J
(P, A)
SODIUM IONnon-polymer23.03Chemie (NA)
6F
(A)
[(~{S})-chloranyl-[[[(2~{R},3~{S},5~{R})-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]methyl]phosphonic acidnon-polymer514.61Chemie (EJH)
7G
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
8H
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
9K, L, M, N
(T, P, D, A)
waterwater18.0161Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight47675.9
Non-Polymers*Number of molecules6
Total formula weight643.4
All*Total formula weight48319.2
*Water molecules are not included.

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PDB entries from 2025-06-11

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