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6G2E

X-ray structure of NSD3-PWWP1 in complex with compound 13

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Histone-lysine N-methyltransferase NSD3polymer13616271.41UniProt (Q9BZ95)
Pfam (PF00855)
Homo sapiens (Human)Nuclear SET domain-containing protein 3,Protein whistle,WHSC1-like 1 isoform 9 with methyltransferase activity to lysine,Wolf-Hirschhorn syndrome candidate 1-like protein 1,WHSC1-like protein 1
2B
(A)
[3,5-dimethyl-4-(1-methyl-5-pyridin-4-yl-imidazol-4-yl)phenyl]methanaminenon-polymer292.41Chemie (EHH)
3C
(A)
waterwater18.084Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight16271.4
Non-Polymers*Number of molecules1
Total formula weight292.4
All*Total formula weight16563.8
*Water molecules are not included.

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PDB entries from 2024-11-20

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