6G0O
Crystal Structure of the first bromodomain of human BRD4 in complex with an acetylated ATRX peptide (K1030ac/K1033ac)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Bromodomain-containing protein 4 | polymer | 127 | 15099.4 | 1 | UniProt (O60885) Pfam (PF00439) In PDB | Homo sapiens (Human) | Protein HUNK1 |
| 2 | B | Transcriptional regulator ATRX | polymer | 11 | 1444.7 | 1 | UniProt (P46100) In PDB | Homo sapiens | ATP-dependent helicase ATRX,X-linked helicase II,X-linked nuclear protein,XNP,Znf-HX |
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | water | water | 18.0 | 168 | Chemie (HOH) |
Sequence modifications
A: 42 - 168 (UniProt: O60885)
B: 1027 - 1037 (UniProt: P46100)
| PDB | External Database | Details |
|---|---|---|
| Met 43 | Thr 43 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Tyr 1037 | Asn 1037 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 16544.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 186.2 | |
| All* | Total formula weight | 16730.3 |
