6G0D
BRD4 (BD1) in complex with APSC-derived ligands (e.g. LY294002)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain-containing protein 4 | polymer | 127 | 15099.4 | 1 | UniProt (O60885) Pfam (PF00439) | Homo sapiens (Human) | Protein HUNK1 |
| 2 | B (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 3 | C (A) | 2-MORPHOLIN-4-YL-7-PHENYL-4H-CHROMEN-4-ONE | non-polymer | 307.3 | 1 | Chemie (LY2) | |||
| 4 | D (A) | water | water | 18.0 | 145 | Chemie (HOH) |
Sequence modifications
A: 42 - 168 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Met 43 | Thr 43 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15099.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 369.4 | |
| All* | Total formula weight | 15468.8 |
