6FZV

Crystal structure of the metalloproteinase enhancer PCPE-1 bound to the procollagen C propeptide trimer (short)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Collagen alpha-1(III) chain	polymer	256	28815.3	3	UniProt (P02461) Pfam (PF01410)	Homo sapiens (Human)
2	D (D)	Procollagen C-endopeptidase enhancer 1	polymer	265	28696.9	1	UniProt (Q15113) Pfam (PF00431)	Homo sapiens (Human)	Procollagen COOH-terminal proteinase enhancer 1,Procollagen C-proteinase enhancer 1,Type 1 procollagen C-proteinase enhancer protein,Type I procollagen COOH-terminal proteinase enhancer
3	E, G, J, M, N (A, B, C, D)	CALCIUM ION	non-polymer		40.1	5	Chemie (CA)
4	F, H, K (A, B, C)	CITRATE ANION	non-polymer		189.1	3	Chemie (FLC)
5	I, L (B, C)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)

Sequence modifications

A, B, C: 1 - 245 (UniProt: P02461)

PDB	External Database	Details
Glu -10	-	expression tag
Thr -9	-	expression tag
Gly -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Ser -1	-	expression tag
Ala 0	-	expression tag
Gln 132	His 1353	variant
Gln 146	Asn 1367	conflict

D: 1 - 253 (UniProt: Q15113)

PDB	External Database	Details
Ala -3	-	expression tag
Pro -2	-	expression tag
Leu -1	-	expression tag
Ala 0	-	expression tag
Ala 254	-	expression tag
Ala 255	-	expression tag
His 256	-	expression tag
His 257	-	expression tag
His 258	-	expression tag
His 259	-	expression tag
His 260	-	expression tag
His 261	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	115142.9
Non-Polymers*	Number of molecules	10
	Total formula weight	838.6
All*	Total formula weight	115981.5

*Water molecules are not included.