6FYO
X-RAY STRUCTURE OF CLK1-KD(148-484)/Cpd-2 AT 2.32A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dual specificity protein kinase CLK1 | polymer | 339 | 39603.5 | 1 | UniProt (P49759) Pfam (PF00069) | Homo sapiens (Human) | CDC-like kinase 1 |
| 2 | B (A) | 6-~{tert}-butyl-~{N}-[6-(1~{H}-pyrazol-4-yl)-1~{H}-imidazo[1,2-a]pyridin-2-yl]pyridine-3-carboxamide | non-polymer | 361.4 | 1 | Chemie (EAQ) | |||
| 3 | C, D, E (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | F (A) | water | water | 18.0 | 144 | Chemie (HOH) |
Sequence modifications
A: 148 - 484 (UniProt: P49759)
| PDB | External Database | Details |
|---|---|---|
| Gly 146 | - | expression tag |
| Pro 147 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39603.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 649.6 | |
| All* | Total formula weight | 40253.1 |
