6FYK
X-Ray structure of CLK2-KD(136-496)/Indazole1 at 2.39A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Dual specificity protein kinase CLK2 | polymer | 363 | 42767.5 | 3 | UniProt (P49760) Pfam (PF00069) | Homo sapiens (Human) | CDC-like kinase 2 |
| 2 | D, E, F (A, B, C) | (2~{S})-4-methyl-1-[5-(3-methyl-2~{H}-indazol-5-yl)pyridin-3-yl]oxy-pentan-2-amine | non-polymer | 324.4 | 3 | Chemie (EAZ) | |||
| 3 | G, H, I (A, B, C) | water | water | 18.0 | 466 | Chemie (HOH) |
Sequence modifications
A, B, C: 136 - 496 (UniProt: P49760)
| PDB | External Database | Details |
|---|---|---|
| Gly 134 | - | expression tag |
| Pro 135 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 128302.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 973.3 | |
| All* | Total formula weight | 129275.8 |
