6FX0
Structure-based design of Trifarotene (CD5789), a potent and selective RAR gamma agonist for the treatment of acne
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Retinoic acid receptor gamma | polymer | 454 | 50404.8 | 1 | UniProt (P13631) Pfam (PF00105) Pfam (PF00104) | Homo sapiens (Human) | RAR-gamma,Nuclear receptor subfamily 1 group B member 3 |
| 2 | B (A) | 6-[3-(1-adamantyl)-4-oxidanyl-phenyl]naphthalene-2-carboxylic acid | non-polymer | 398.5 | 1 | Chemie (E9T) | |||
| 3 | C (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 4 | D (A) | water | water | 18.0 | 294 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 50404.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 592.7 | |
| All* | Total formula weight | 50997.6 |
