6FUL
Crystal structure of UTX complexed with 5-hydroxy-4-keto-1-methyl-picolinate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Lysine-specific demethylase 6A | polymer | 531 | 60264.4 | 1 | UniProt (O15550) Pfam (PF02373) Pfam (PF21322) Pfam (PF21326) | Homo sapiens (Human) | Histone demethylase UTX,Ubiquitously-transcribed TPR protein on the X chromosome,Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein |
| 2 | B (A) | 1-methyl-5-oxidanyl-4-oxidanylidene-pyridine-2-carboxylic acid | non-polymer | 169.1 | 1 | Chemie (E7Z) | |||
| 3 | C (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 4 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | E, F, G, H, I... (A) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 6 | K (A) | 2-(2-METHOXYETHOXY)ETHANOL | non-polymer | 120.1 | 1 | Chemie (PG0) | |||
| 7 | L (A) | water | water | 18.0 | 627 | Chemie (HOH) |
Sequence modifications
A: 877 - 1401 (UniProt: O15550)
| PDB | External Database | Details |
|---|---|---|
| Gly 871 | - | expression tag |
| Pro 872 | - | expression tag |
| Gly 873 | - | expression tag |
| Tyr 874 | - | expression tag |
| Gln 875 | - | expression tag |
| Asp 876 | - | expression tag |
| Asn 878 | Ser 878 | conflict |
| Ser 879 | Pro 879 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 60264.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 986.0 | |
| All* | Total formula weight | 61250.4 |
