6FUH
Complement factor D in complex with the inhibitor (4-((3-(aminomethyl)phenyl)amino)quinazolin-2-yl)-L-valine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Complement factor D | polymer | 232 | 24739.1 | 1 | UniProt (P00746) Pfam (PF00089) In PDB | Homo sapiens (Human) | Adipsin,C3 convertase activator,Properdin factor D |
2 | A | (2~{S})-2-[[4-[[3-(aminomethyl)phenyl]amino]quinazolin-2-yl]amino]-3-methyl-butanoic acid | non-polymer | 365.4 | 1 | Chemie (E88) | |||
3 | water | water | 18.0 | 250 | Chemie (HOH) |
Sequence modifications
A: 16 - 243 (UniProt: P00746)
PDB | External Database | Details |
---|---|---|
Ser 244 | - | expression tag |
Ala 245 | - | expression tag |
Ala 246 | - | expression tag |
Ala 247 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 24739.1 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 365.4 | |
All* | Total formula weight | 25104.5 |