6FTX
Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone H3 | polymer | 97 | 11431.4 | 1 | UniProt (S4RAZ3) Pfam (PF00125) | Petromyzon marinus (Sea lamprey) | |
| 2 | B, F (B, F) | Histone H4 | polymer | 103 | 11394.4 | 2 | UniProt (P62799) Pfam (PF15511) | Xenopus laevis (African clawed frog) | |
| 3 | C, G (C, G) | Histone H2A type 1 | polymer | 130 | 14093.4 | 2 | UniProt (P06897) Pfam (PF00125) Pfam (PF16211) | Xenopus laevis (African clawed frog) | |
| 4 | D, H (D, H) | Histone H2B | polymer | 126 | 13939.2 | 2 | UniProt (F6TNY0) Pfam (PF00125) UniProt (by SIFTS) (Q28D68) | Xenopus tropicalis (Western clawed frog) | |
| 5 | E (E) | Histone H3.3C | polymer | 110 | 12329.3 | 1 | UniProt (P02302) Pfam (PF00125) | Xenopus laevis (African clawed frog) | |
| 6 | I (I) | DNA (159-MER) | polymer | 159 | 48792.1 | 1 | synthetic construct | ||
| 7 | J (J) | DNA (160-MER) | polymer | 160 | 49678.6 | 1 | synthetic construct | ||
| 8 | K, L (N, O) | Polyubiquitin-B | polymer | 76 | 8576.8 | 2 | UniProt (P0CG47) Pfam (PF00240) | Homo sapiens (Human) | |
| 9 | M (W) | Chromatin-remodeling ATPase | polymer | 878 | 102152.9 | 1 | Pfam (PF00271) Pfam (PF18196) Pfam (PF00385) Pfam (PF00176) UniProt (by SIFTS) (P32657) | Saccharomyces cerevisiae (Baker's yeast) | |
| 10 | N (W) | BERYLLIUM TRIFLUORIDE ION | non-polymer | 66.0 | 1 | Chemie (BEF) | |||
| 11 | O (W) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) |
Sequence modifications
C, G: 0 - 129 (UniProt: P06897)
E: 29 - 135 (UniProt: P02302)
| PDB | External Database | Details |
|---|---|---|
| Arg 99 | Gly 100 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 26 | - | expression tag |
| Ala 27 | - | expression tag |
| Ala 28 | - | expression tag |
| Ala 30 | Pro 31 | conflict |
| Ala 32 | Thr 33 | conflict |
| Ala 33 | Gly 34 | conflict |
| Ala 34 | Gly 35 | conflict |
| Ala 35 | Val 36 | conflict |
| Ala 36 | Lys 37 | conflict |
| Ala 37 | Lys 38 | conflict |
| Ala 38 | Pro 39 | conflict |
| Ser 86 | Arg 87 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 13 |
| Total formula weight | 320392.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 493.2 | |
| All* | Total formula weight | 320885.3 |
